Research Project
Abstract
Isolation and characterization of organic compounds from Momordica charantia “Cundeamor” Infusion used for Diabetes Type II in Puerto Rico
Jessica Torres Kolbus; Elba D. Reyes, PhD
From the Department of Chemistry, University of Puerto Rico at Cayey, Cayey, Puerto Rico, 00736
Momordica charantia L., locally known as Cundeamor, is being widely used as tea to decrease [...]
Read Full Post | Make a Comment ( None so far )Progreso
De los objetivos establecidos en enero podría decir que prácticamente he alcanzado un 50% del progreso. Debido ha que he estado optimizando la metodología al momento no me he encontrado con dificultades experimentales, excepto en el sentido de que los materiales han comenzado a limitarse según la investigación lleva más de un año en progreso. [...]
Read Full Post | Make a Comment ( None so far )Plan de trabajo: Ultimo semestre
Este es el ultimo semestre en el que estare trabajando para BioMinds. Mi mentora y yo esperamos lograr obtener analisis de identificacion y caracterizacion mas definidos.
Para ello trabajare con las infusiones de la planta Cundeamor y realizare comparacion con extarccion sohxlet. Esto nos permitrira ademas, realizar comparacion con la literatura.
Se continuara optimizando la metodologia basandonos [...]
Results and Future Work
During this semester I was able to work with three different extracts of Cundeamor: the crude extract, the Sohxlet extract and the infusion. My results show that organic compounds are being extracted in each by solvents of different polarities. Also, as expected, a major quantity of constituens are extracted in the crudes. We should work [...]
Read Full Post | Make a Comment ( None so far )About Progress and Contribution
In the scale of 1 to 5, this time I describe my project with a 4 by having more or less 80% of our objectives accomplished. I have optimized most of the mixture of solvents and we have analyzed most of the sample extracts by NMR. Also, I’ve been optimizing the quantities of leaves used [...]
Read Full Post | Make a Comment ( None so far )New technique and more progress!!!
During this semester I had progress in my project and hence I have learned a new technique. This technique is column chromatography and we use it to isolate compounds from the plant Cundeamor extract, to later analyze by spectroscopic methods. In column chromatography, the stationary phase, a solid adsorbent, for which we use silica, is placed [...]
Read Full Post | Make a Comment ( None so far )Research Plan for the 2nd Semester
During the first semester I was able to work out the infusion and crude extract of the plant under study. I basically developed the first stage of the methodology but I still need to optimize the method for identification of compounds in each fraction by selecting the best mixture of solvents by TLC. This is [...]
Read Full Post | Make a Comment ( 5 so far )Mi experiencia….. (enero-mayo 2008)
Durante este semestre he tenido la oportunidad de aprender varias técnicas de laboratorio, las cuales ya he mencionado. Pero creo que también es muy importante el hecho de adquirir experiencia en el laboratorio de forma individual, ya que de esta forma uno aprende más a tener pensamiento crítico y analizar de forma independiente; claro está, [...]
Read Full Post | Make a Comment ( 1 so far )Tecnicas de Lab
Este semestre ha sido uno de mucho aprendizaje y práctica gracias a la experiencia de investigación que estoy llevando a cabo con la Dra. Elba Reyes. Para propósitos de nuestra investigación he logrado trabajar con diversas técnicas para aislar componentes a partir de la infusión de una planta. Para ello he llevado a cabo técnicas [...]
Read Full Post | Make a Comment ( None so far )Isolation and Characterization of Organic Compounds from Medicinal Plants Infusions and Crude Extracts used for Diabetes Type II in Puerto Rico
Diabetes Mellitus is an endocrine disorder caused by a deficiency of insulin (pancreatic hormone which sends a signal to cells for the uptake and storage of glucose) or a decreased response to insulin in target tissues. There are 2 types of diabetes, with different causes but each is marked by high-blood glucose, effect that [...]
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